Substance Misuse

Mayor Hancock speaking at overdose awareness day event

Substance misuse and overdose are an increasing community health concern across the city of Denver. The DDPHE Community & Behavioral Health division is the coordinating agency addressing opioid and other substance misuse in Denver. The division utilizes a collective impact model to engage stakeholders across disciplines to achieve a common goal.

*For Information about the installation of sharps disposal kiosks and locations, select Syringe & Medication Collection below*

Collective Impact

The rising opioid epidemic in Denver necessitates a coordinated and comprehensive response that draws on the expertise of service providers, policymakers and systems-level actors. The response must allocate sufficient resources for the delivery of individual services and for the alignment, coordination and systems development that will ensure those services have the maximum impact.

Denver’s Department of Public Health & Environment (DDPHE) initiated a collective impact process to coordinate the multi-sectoral efforts underway to address the opioid epidemic. The Collective Impact Group (CIG) is also working closely with leadership at the state level and in various other areas in Colorado, Seattle/King County, San Francisco, and Vancouver to benefit from lessons learned and common approaches to reducing opioid misuse.

Learn more about Denver's Collective Impact efforts below:


Resources and Crisis Services


The presence of fentanyl has led to epidemic levels of overdoses here in Denver and other parts of the country, including New York City. 

Learn more about Fentanyl 

Syringe and Medication Disposal

Denver Public Health & Environment (DDPHE) recently completed the installation of four sharps disposal kiosks to address the issue of discarded syringes in public spaces.

Learn more about sharp kiosks and where they are located