Mayor's Youth Commission applications are open year-round and interviews are held in late April of each year. Selected commissioners can serve up to a three-year term limit and are required to attend meetings that are scheduled during the evening, the 1st and 3rd Wednesday of each month, during the school year. To qualify:
- Youth must be a Denver resident or attending Denver Public Schools (high school) in 2021-2022.
- Adults must be employed with a youth-serving organization or the City and County of Denver.