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Substance Misuse & Overdose Prevention

Substance misuse and overdose are an increasing community health concern across the city of Denver. The DDPHE Community Health division is the coordinating agency addressing opioid and other substance misuse in Denver. The division utilizes a collective impact model to engage stakeholders across disciplines to achieve a common goal.




The rising opioid epidemic in Denver necessitates a coordinated and comprehensive response that draws on the expertise of service providers, policymakers and systems-level actors. The response must allocate sufficient resources for the delivery of individual services and for the alignment, coordination and systems development that will ensure those services have the maximum impact.

Denver’s Department of Public Health & Environment (DDPHE) initiated a collective impact process to coordinate the multi-sectoral efforts underway to address the opioid epidemic. The Collective Impact Group (CIG) is also working closely with leadership at the state level and in various other areas in Colorado, Seattle/King County, San Francisco, and Vancouver to benefit from lessons learned and common approaches to reducing opioid misuse.

Learn more about Denver's Collective Impact efforts below:


If you find needles or syringes on public property, please call 311 and do not handle the needles or syringes yourself.

To dispose of used needles, see locations below:


  1. City kiosk on the River by 14th Ave. and Speer
  2. King Soopers parking lot at Speer and 13th Ave.
  3. Access Point/Colorado AIDS Project: 6260 East Colfax (Please call in advance to ensure staff is available to assist in disposal)
  4. Harm Reduction Action Center (HRAC): 231 East Colfax, Monday - Friday, 9:00 a.m. to 12:00 p.m., 303-572-7800

Learn more about needle disposal locations outside of Denver.


Locations for Medication Disposal:

Learn more medication disposal locations and what medications are accepted.

Learn more about the importance of safe medication disposal.

Find medication disposal locations throughout Denver metro.


Regional Syringe Access Programs


Harm Reduction Action Center (HRAC)

Location: 231 E. Colfax Ave. Denver, CO 80203

Hours: Monday – Friday, 9 a.m. to 12:00 p.m.

Phone: 303-572-7800

Access Point/Colorado AIDS Project

Location: 6260 E. Colfax Ave., Denver, CO 80207

Hours: Monday – Thursday 1:00 p.m. to 6:00 p.m., Friday 12:00 p.m. to 3:00 p.m.

Phone: 303-837-1501 ext. 5321


Find syringe access programs in your county.

Find more syringe disposal locations across Colorado.

Substance Abuse and Mental Health Services Administration (SAMHSA) Directory for Medication Assisted Treatment.

Statewide Mental Health Resources

Treatment Information

Statewide Crisis line: 1-844-493-8255 or text “TALK” to 38255



Marion Rorke, MPH - Substance Use Resource Coordinator
DDPHE - Community Health Division
O: 720-865-5453 / C: 720-422-1617



Denver 311 Help Center Call 3-1-1
Outside Denver Call 720-913-1311
Emergencies: 911 
TTY Service: 720-913-8479